3-oxoacyl-[acyl-carrier-protein] synthase activity

ID: GO_0004315

Class

Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].

Note that this activity is responsible for the chain-elongation step of dissociated (type II) fatty-acid biosynthesis, i.e. the addition of two C atoms to the fatty-acid chain. Can use fatty acyl thioesters of ACP (C2 to C16) as substrates, as well as fatty acyl thioesters of Co-A (C4 to C16).

Open in VFB 3D Browser →

Classification

Alternative Names

SynonymScopeReference
acyl-malonyl acyl carrier protein-condensing enzyme activityrelated synonym2.3.1.41
beta-ketoacyl acyl carrier protein synthase activityrelated synonym2.3.1.41
3-oxoacyl-acyl-carrier-protein synthase activityrelated synonym2.3.1.41
acyl-malonyl(acyl-carrier-protein)-condensing enzyme activityrelated synonym2.3.1.41
acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)related synonym2.3.1.41
beta-ketoacyl-ACP synthetase activityrelated synonym2.3.1.41
beta-ketoacyl-[acyl carrier protein] synthase activityrelated synonym2.3.1.41
beta-ketoacyl-acyl carrier protein synthetase activityrelated synonym2.3.1.41
beta-ketoacyl synthetase activityrelated synonym2.3.1.41
beta-ketoacylsynthase activityrelated synonym2.3.1.41
3-ketoacyl-acyl carrier protein synthase activityrelated synonym2.3.1.41
beta-ketoacyl-acyl carrier protein synthase activityrelated synonym2.3.1.41
beta-ketoacyl-acyl-carrier-protein synthase II activitynarrow synonym
3-oxoacyl-acyl carrier protein synthase I activitynarrow synonym2.3.1.179
beta-ketoacyl-ACP synthase II activitynarrow synonym2.3.1.179
beta-ketoacyl-acyl-carrier-protein synthase Inarrow synonym2.3.1.41
beta-ketoacyl-ACP synthase I activitynarrow synonym2.3.1.41
condensing enzyme activitybroad synonym2.3.1.41
fatty acid condensing enzyme activitybroad synonym2.3.1.41
ketoacyl-ACP synthase activityexact synonym
3-oxoacyl-[acyl-carrier protein] synthase activityexact synonym
3-oxoacyl-ACP synthase activityexact synonym

References