cytochrome-c oxidase activity GO_0004129
cytochrome-c oxidase activity
ID: GO_0004129
Class
Catalysis of the reaction: 4 Fe(II)-[cytochrome c] + O2 + 8 H+(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H+(out).
The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
Open in VFB 3D Browser →Classification
- active monoatomic ion transmembrane transporter activity
- electron transfer activity
- oxidoreductase activity, acting on a heme group of donors
- oxidoreduction-driven active transmembrane transporter activity
- proton transmembrane transporter activity
Relationships
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| Warburg’s respiratory enzyme activity | related synonym | 7.1.1.9 |
| complex IV (mitochondrial electron transport) activity | related synonym | 7.1.1.9 |
| cytochrome oxidase activity | related synonym | 7.1.1.9 |
| aa3-type cytochrome c oxidase | narrow synonym | 7.1.1.9 |
| caa3-type cytochrome c oxidase | narrow synonym | 7.1.1.9 |
| indophenol oxidase | narrow synonym | |
| ba3-type cytochrome c oxidase | narrow synonym | 7.1.1.9 |
| cytochrome aa3 activity | narrow synonym | 7.1.1.9 |
| indophenolase | narrow synonym | |
| cytochrome a3 activity | narrow synonym | 7.1.1.9 |
| cbb3-type cytochrome c oxidase | narrow synonym | 7.1.1.9 |
| cytochrome c oxidase activity | exact synonym |