histone H2AQ104 methyltransferase activity GO_1990259

histone H2AQ104 methyltransferase activity

ID: GO_1990259

Catalysis of the reaction: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine + H+. Note that this corresponds to Q105 in yeast.

Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Note that this resudue is missing from the H2AZ clade. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.