histone H3K27 methyltransferase activity GO_0046976
histone H3K27 methyltransferase activity
ID: GO_0046976
Class
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group to the lysine residue at position 27 of the histone H3 protein.
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| histone methyltransferase activity (H3-K27 specific) | exact synonym | |
| histone methylase activity (H3-K27 specific) | exact synonym | mah |
| histone H3K27 methylase activity | exact synonym | |
| histone methylase activity (H3-K56 specific) | exact synonym | |
| histone lysine N-methyltransferase activity (H3-K27 specific) | exact synonym | |
| histone-H3K27 methyltransferase activity | exact synonym |