histone H3K36me2/H3K36me3 demethylase activity GO_0140681
histone H3K36me2/H3K36me3 demethylase activity
ID: GO_0140681
Class
Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| histone H3K36me2 demethylase activity | broad synonym | |
| histone H3-tri/dimethyl-lysine-36 demethylase activity | exact synonym | |
| histone H3K36me3 demethylase activity | related synonym |