histone H4K20 monomethyltransferase activity GO_0140944
histone H4K20 monomethyltransferase activity
ID: GO_0140944
Class
Catalysis of the reaction: L-lysyl20-[histone H4] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl20-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 20 of histone H4, producing histone H4K20me.
Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| histone H4K20 methylase activity | broad synonym | |
| histone H4-K20 methylation | broad synonym | |
| histone H4K20 methylation | broad synonym | |
| histone H4K20 monomethylation | exact synonym | |
| histone lysine N-monomethyltransferase activity (H4-K20 specific) | exact synonym |