I-kappaB phosphorylation [GO_0007252]

The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
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I-kappaB phosphorylation

ID: GO_0007252

Class

The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

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Alternative Names

Synonym Scope Reference
inhibitor of NF-kappaB phosphorylation exact synonym bf
IKB phosphorylation exact synonym bf
IkappaB phosphorylation exact synonym bf
inhibitor of kappaB phosphorylation exact synonym bf

References