IkappaB kinase activity GO_0008384
IkappaB kinase activity
ID: GO_0008384
Class
Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.
Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.
Open in VFB 3D Browser →Classification
Relationships
- is part of: I-kappaB phosphorylation
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| IKK | related synonym | 2.7.11.10 |
| IKBKA | related synonym | 2.7.11.10 |
| inhibitor of NFkappaB kinase activity | related synonym | 2.7.11.10 |
| inhibitor of NF-kappaB kinase activity | related synonym | 2.7.11.10 |
| IKBKB | related synonym | 2.7.11.10 |
| IKK-2 | related synonym | 2.7.11.10 |
| IKK-1 | related synonym | 2.7.11.10 |
| STK12 | related synonym | 2.7.11.10 |
| ATP:IkappaB protein phosphotransferase activity | related synonym | 2.7.11.10 |
| TBK1 | related synonym | 2.7.11.10 |
| CHUK | related synonym | 2.7.11.10 |
| TANK-binding kinase 1 activity | narrow synonym | 2.7.11.10 |