inositol-3-phosphate synthase activity GO_0004512
inositol-3-phosphate synthase activity
ID: GO_0004512
Class
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| D-glucose 6-phosphate cycloaldolase activity | related synonym | 5.5.1.4 |
| glucose-6-phosphate inositol monophosphate cycloaldolase activity | related synonym | 5.5.1.4 |
| 1L-myo-inositol-1-phosphate lyase (isomerizing) | related synonym | 5.5.1.4 |
| glucocycloaldolase activity | related synonym | 5.5.1.4 |
| inositol 1-phosphate synthatase activity | related synonym | 5.5.1.4 |
| inositol 1-phosphate synthetase activity | related synonym | 5.5.1.4 |
| glucose 6-phosphate cyclase activity | related synonym | 5.5.1.4 |