L-glutamate gamma-semialdehyde dehydrogenase activity GO_0003842
L-glutamate gamma-semialdehyde dehydrogenase activity
ID: GO_0003842
Class
L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + 2 H+.
(S)-1-pyrroline-5-carboxylate is in spontaneous equilibrium with its tautomer L-glutamate gamma-semialdehyde. The activity can also oxidize other 1-pyrrolines, e.g. oxidation of 3-hydroxy-1-pyrroline-5-carboxylate to 4-hydroxyglutamate, and oxidation of (R)-1-pyrroline-5-carboxylate to D-glutamate.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| delta1-pyrroline-5-carboxylate dehydrogenase activity | related synonym | 1.2.1.88 |
| pyrroline-5-carboxylic acid dehydrogenase activity | related synonym | 1.2.1.88 |
| 1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity | related synonym | |
| 1-pyrroline-5-carboxylate dehydrogenase activity | related synonym | |
| L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity | related synonym | |
| pyrroline-5-carboxylate dehydrogenase activity | related synonym | 1.2.1.88 |
| 1-pyrroline dehydrogenase | broad synonym |