MAP kinase activity GO_0004707
MAP kinase activity
ID: GO_0004707
Class
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
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Relationships
- is part of: MAPK cascade
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| MAPK | related synonym | 2.7.11.24 |
| ERK | related synonym | 2.7.11.24 |
| ERK2 | related synonym | |
| mitogen-activated protein kinase activity | related synonym | 2.7.11.24 |
| ATP:protein phosphotransferase (MAPKK-activated) activity | related synonym | 2.7.11.24 |
| MAP kinase 2 activity | narrow synonym | |
| extracellular signal-regulated kinase activity | narrow synonym | 2.7.11.24 |
| MBP kinase II activity | narrow synonym | 2.7.11.24 |
| myelin basic protein kinase activity | narrow synonym | 2.7.11.24 |
| SAPK | narrow synonym | |
| MAP kinase 1 activity | narrow synonym | |
| stress-activated kinase activity | narrow synonym | |
| SAP kinase activity | narrow synonym | |
| stress-activated protein kinase activity | narrow synonym | |
| MBP kinase I activity | narrow synonym | 2.7.11.24 |
| ERK1 | exact synonym | |
| mitogen activated kinase activity | exact synonym |