antennal mechanosensory and motor center A2 projection neuron [FBbt_00110124]

Projection neuron whose cell body is located dorsally to the antennal mechanosensory and motor center (AMMC). It projects to the ipsilateral inferior ventrolateral protocerebrum (IVLP) region and AMMC zones A and B. It also projects contralaterally via the inferior AMMC commissure to arborize in the AMMC zones A and B. Its dendrites receive input in the AMMC zone A and establish postsynaptic connections in the IVLP. These neurons are broadly tuned to respond to 100, 300 Hz, 700Hz or pulse song stimuli (Lai et al., 2012). Auditory function was determined measuring GCaMP activation in these cells in response to an acoustic stimuli in a subset of neurons labeled with VT30609-GAL4. This driver also labels AMMC-B1b neurons, although these two types can be distinguished by its acoustic response: only AMMC-A2 neurons respond to 700Hz stimuli. Presence of pre- and postsynaptic sites was determined by immunoreactivity to Dscam- and synaptotagmin-GFP localization, respectively (Lai et al., 2012).

Open antennal mechanosensory and motor center A2 projection neuron in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110124",
            "symbol": "",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110124",
            "label": "antennal mechanosensory and motor center A2 projection neuron"
        },
        "description": [
            "Projection neuron whose cell body is located dorsally to the antennal mechanosensory and motor center (AMMC). It projects to the ipsilateral inferior ventrolateral protocerebrum (IVLP) region and AMMC zones A and B. It also projects contralaterally via the inferior AMMC commissure to arborize in the AMMC zones A and B. Its dendrites receive input in the AMMC zone A and establish postsynaptic connections in the IVLP. These neurons are broadly tuned to respond to 100, 300 Hz, 700Hz or pulse song stimuli (Lai et al., 2012)."
        ],
        "comment": [
            "Auditory function was determined measuring GCaMP activation in these cells in response to an acoustic stimuli in a subset of neurons labeled with VT30609-GAL4. This driver also labels AMMC-B1b neurons, although these two types can be distinguished by its acoustic response: only AMMC-A2 neurons respond to 700Hz stimuli. Presence of pre- and postsynaptic sites was determined by immunoreactivity to Dscam- and synaptotagmin-GFP localization, respectively (Lai et al., 2012)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110119",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110119",
            "label": "antennal mechanosensory and motor center A projection neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110127",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110127",
            "label": "auditory system neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00045027",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00045027",
                "label": "wedge"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013001",
                "label": "has_synaptic_IO_in",
                "type": "has_synaptic_IO_in"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00100016",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00100016",
                "label": "antennal mechanosensory and motor center zone B"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00110123",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00110123",
                "label": "cell body rind of adult ventrolateral protocerebrum"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002101",
                "label": "fasciculates with",
                "type": "fasciculates_with"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00110184",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Neuron_projection_bundle"
                ],
                "short_form": "FBbt_00110184",
                "label": "inferior AMMC commissure"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0000053",
                "label": "bearer of",
                "type": "bearer_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/PATO_0000618",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "PATO_0000618",
                "label": "bilateral"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "AMMC-A2 neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0217491",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0217491",
                    "label": "Lai et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(7): 2607--2612"
                },
                "FlyBase": "",
                "PubMed": "22308412",
                "DOI": "10.1073/pnas.1117307109"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "AMMC-A2 PN",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0217491",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0217491",
                    "label": "Lai et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(7): 2607--2612"
                },
                "FlyBase": "",
                "PubMed": "22308412",
                "DOI": "10.1073/pnas.1117307109"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0217491",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0217491",
                "label": "Lai et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(7): 2607--2612"
            },
            "FlyBase": "",
            "PubMed": "22308412",
            "DOI": "10.1073/pnas.1117307109"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0230862",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0230862",
                "label": "Matsuo et al., 2016, J. Comp. Neurol. 524(6): 1099--1164"
            },
            "FlyBase": "FBrf0230862",
            "PubMed": "26762251",
            "DOI": "10.1002/cne.23955"
        }
    ]
}