anterior escort cell [FBbt_00048535]

Cell belonging to the anterior-most population of escort cells, adjacent to the cap cells (Eliazer et al., 2014). They display shorter and less elaborate extensions than other escort cells (Banisch et al., 2017) and respond to Hedgehog protein secreted from the cap cells to maintain the germline stem cells (Rojas-Rios et al., 2012). Can be distinguished from other escort cell subtypes based on expression of hh and Pdk1 and lack of GstS1 expression (Rust et al., 2020).
Tags:

Open anterior escort cell in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00048535",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00048535",
            "label": "anterior escort cell"
        },
        "description": [
            "Cell belonging to the anterior-most population of escort cells, adjacent to the cap cells (Eliazer et al., 2014). They display shorter and less elaborate extensions than other escort cells (Banisch et al., 2017) and respond to Hedgehog protein secreted from the cap cells to maintain the germline stem cells (Rojas-Rios et al., 2012)."
        ],
        "comment": [
            "Can be distinguished from other escort cell subtypes based on expression of hh and Pdk1 and lack of GstS1 expression (Rust et al., 2020)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00006049",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00006049",
            "label": "escort cell"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0020386",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgn0020386",
                "label": "Pdk1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0004644",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgn0004644",
                "label": "hh"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "anterior EC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0247148",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0247148",
                    "label": "Rust et al., 2020, Nat. Commun. 11(1): 5628"
                },
                "FlyBase": "",
                "PubMed": "33159074",
                "DOI": "10.1038/s41467-020-19361-0"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "anterior inner germarial sheath cell",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aEC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0247148",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0247148",
                    "label": "Rust et al., 2020, Nat. Commun. 11(1): 5628"
                },
                "FlyBase": "",
                "PubMed": "33159074",
                "DOI": "10.1038/s41467-020-19361-0"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aIGS",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0224400",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0224400",
                "label": "Eliazer et al., 2014, PLoS Genet. 10(3): e1004200"
            },
            "FlyBase": "",
            "PubMed": "24625679",
            "DOI": "10.1371/journal.pgen.1004200"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0235678",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0235678",
                "label": "Banisch et al., 2017, Development 144(11): 1937--1947"
            },
            "FlyBase": "",
            "PubMed": "28559239",
            "DOI": "10.1242/dev.143727"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0218031",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0218031",
                "label": "Rojas-R\u00edos et al., 2012, PLoS Biol. 10(4): e1001298"
            },
            "FlyBase": "",
            "PubMed": "22509132",
            "DOI": "10.1371/journal.pbio.1001298"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0247148",
                "types": [
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                ],
                "short_form": "FBrf0247148",
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            },
            "FlyBase": "",
            "PubMed": "33159074",
            "DOI": "10.1038/s41467-020-19361-0"
        }
    ]
}