dorsal organ warming cell [FBbt_00051986]

Ir68a, Ir25a and Ir93a -expressing neuron of the dorsal organ ganglion (DOG), activated by temperature increases (Hernandez-Nunez et al., 2021). All three of these Ir genes are necessary for heating-induced activity of these cells, with Ir68a specifying warming, rather than cooling sensitivity (Hernandez-Nunez et al., 2021). Two of these cells are found in each DOG and each projects to a different antennal lobe glomerulus, distinct from the one targeted by the cool cells, in the posterior dorsal antennal lobe (Hernandez-Nunez et al., 2021). The sensory dendrites of these neurons do not exhibit the membrane infoldings seen in the cool cells and they extend a thin dendrite into the central dome sensillum (Hernandez-Nunez et al., 2021).

Open dorsal organ warming cell in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00051986",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron",
                "Sensory_neuron"
            ],
            "short_form": "FBbt_00051986",
            "label": "dorsal organ warming cell"
        },
        "description": [
            "Ir68a, Ir25a and Ir93a -expressing neuron of the dorsal organ ganglion (DOG), activated by temperature increases (Hernandez-Nunez et al., 2021). All three of these Ir genes are necessary for heating-induced activity of these cells, with Ir68a specifying warming, rather than cooling sensitivity (Hernandez-Nunez et al., 2021). Two of these cells are found in each DOG and each projects to a different antennal lobe glomerulus, distinct from the one targeted by the cool cells, in the posterior dorsal antennal lobe (Hernandez-Nunez et al., 2021). The sensory dendrites of these neurons do not exhibit the membrane infoldings seen in the cool cells and they extend a thin dendrite into the central dome sensillum (Hernandez-Nunez et al., 2021)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00047188",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron",
                "Sensory_neuron"
            ],
            "short_form": "FBbt_00047188",
            "label": "dorsal organ sensory neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00051294",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron",
                "Sensory_neuron"
            ],
            "short_form": "FBbt_00051294",
            "label": "larval thermosensory neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00007153",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Larva",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00007153",
                "label": "embryonic/larval antennal lobe glomerulus"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00007227",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Ganglion",
                    "Larva",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00007227",
                "label": "dorsal organ ganglion"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013007",
                "label": "has_sensory_dendrite_in",
                "type": "has_sensory_dendrite_in"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00007189",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Larva",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00007189",
                "label": "dorsal organ dome sensillum"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0036150",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgn0036150",
                "label": "Ir68a"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002215",
                "label": "capable of",
                "type": "capable_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0120168",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0120168",
                "label": "detection of hot stimulus involved in thermoception"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "larval WC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0250348",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0250348",
                    "label": "Hernandez-Nunez et al., 2021, Sci. Adv. 7(35): eabg6707"
                },
                "FlyBase": "",
                "PubMed": "34452914",
                "DOI": "10.1126/sciadv.abg6707"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "larval warming cell",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0250348",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0250348",
                    "label": "Hernandez-Nunez et al., 2021, Sci. Adv. 7(35): eabg6707"
                },
                "FlyBase": "",
                "PubMed": "34452914",
                "DOI": "10.1126/sciadv.abg6707"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0250348",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0250348",
                "label": "Hernandez-Nunez et al., 2021, Sci. Adv. 7(35): eabg6707"
            },
            "FlyBase": "",
            "PubMed": "34452914",
            "DOI": "10.1126/sciadv.abg6707"
        }
    ]
}