lamina wide-field 1 neuron [FBbt_00003741]
An intrinsic columnar neuron of the visual system whose cell body is located in the medulla cortex and that has a main projection that ascends via the first optic chiasm into the lamina where it is restricted to a single column for most of its length before making wide-field arborizations in the distal lamina. These neurons also arborize on the distal surface of the medulla in a circular field of about 20 columns. Several linking fibers from this arborization descend into M4 where they form a wide arborization field covering about 30-40 columns (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In the lamina, it forms numerous presynaptic connections to lamina monopolar neuron L3 and lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011). These neurons along with the lamina wide-field 2 neurons express the transcription factor Fer2 (Ozel et al., 2021). They are cholinergic (Davis et al., 2020). Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt}) [FBtp0015803]. The identification of dendrites and axons was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP}) [FBtp0021447] or a UAS-tau (P{UAS-tau-lacZ.O}) [FBtp0010033] reporter, respectively (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lawf (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (1/1), R2 (3/-), R3 (1/-), R6 (1/-), L1 (1/-), L2 (7/-), L3 (17/-), L5 (1/-), Lai (24/-), T1 (1/-), C2 (3/-), C3 (2/-), Lawf collaterals (5) and epithelial glia (6/-) (Rivera-Alba et al., 2011).
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen lamina wide-field 1 neuron in VFB
VFB Term Json
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"label": "has soma location",
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"label": "cell body rind of adult medulla"
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