lamina wide-field 2 neuron [FBbt_00110065]

An intrinsic columnar neuron of the visual system whose cell body is located in the medulla cortex and that has a main projection into the lamina making wide-field arborizations in the distal lamina, innervating 28 cartridges. These neurons also arborize in the medulla (Hasegawa et al., 2011). In the M1 layer, the branches are large and overlapping, encompassing around 120 cartridges. In medulla layers M8 to M10 the branches are smaller, encompassing around 17 cartridges and show less overlap. Putative cholinergic presynaptic sites are observed in the lamina. These neurons along with the lamina wide-field 1 neurons express the transcription factor Fer2.

Open lamina wide-field 2 neuron in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110065",
            "symbol": "Lawf2",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Cholinergic",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110065",
            "label": "lamina wide-field 2 neuron"
        },
        "description": [
            "An intrinsic columnar neuron of the visual system whose cell body is located in the medulla cortex and that has a main projection into the lamina making wide-field arborizations in the distal lamina, innervating 28 cartridges. These neurons also arborize in the medulla (Hasegawa et al., 2011). In the M1 layer, the branches are large and overlapping, encompassing around 120 cartridges. In medulla layers M8 to M10 the branches are smaller, encompassing around 17 cartridges and show less overlap. Putative cholinergic presynaptic sites are observed in the lamina. These neurons along with the lamina wide-field 1 neurons express the transcription factor Fer2."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058205",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Cholinergic",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058205",
            "label": "adult cholinergic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00007578",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00007578",
            "label": "intrinsic columnar neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003708",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00003708",
                "label": "lamina"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003759",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003759",
                "label": "medulla layer M9"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003760",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003760",
                "label": "medulla layer M10"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003758",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003758",
                "label": "medulla layer M8"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003750",
                "label": "medulla layer M1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00100205",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00100205",
                "label": "cell body rind of adult medulla"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0038402",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgn0038402",
                "label": "Fer2"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Lawfl2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0213020",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0213020",
                    "label": "Hasegawa et al., 2011, Development 138(5): 983--993"
                },
                "FlyBase": "",
                "PubMed": "21303851",
                "DOI": "10.1242/dev.058370"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Lawf2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0225131",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0225131",
                    "label": "Tuthill et al., 2014, Neuron 82(4): 887--895"
                },
                "FlyBase": "",
                "PubMed": "24853944",
                "DOI": "10.1016/j.neuron.2014.04.023"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0225131",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0225131",
                "label": "Tuthill et al., 2014, Neuron 82(4): 887--895"
            },
            "FlyBase": "",
            "PubMed": "24853944",
            "DOI": "10.1016/j.neuron.2014.04.023"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0213020",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0213020",
                "label": "Hasegawa et al., 2011, Development 138(5): 983--993"
            },
            "FlyBase": "",
            "PubMed": "21303851",
            "DOI": "10.1242/dev.058370"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0247762",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0247762",
                "label": "\u00d6zel et al., 2021, Nature 589(7840): 88--95"
            },
            "FlyBase": "",
            "PubMed": "33149298",
            "DOI": "10.1038/s41586-020-2879-3"
        }
    ]
}