larval down and back neuron [FBbt_00047725]

Cholinergic somatosensory interneuron that arborizes in the nociceptive neuropil and receives input from class IV dendritic arborizing neurons (Gerhard et al., 2017; Burgos et al., 2018). From a laterally-located cell body, it projects ventromedially to the nociceptive neuropil and arborizes profusely; then a single process projects back laterally and dorsally towards the cell body (Burgos et al., 2018). It is involved in activating bending and rolling behavior in response to nociceptive stimuli, such as noxious heat (Burgos et al., 2018) and it is a premotor neuron (Zarin et al., 2019). DnBs seem to have peptidergic output sites, but peptide identity unknown (Burgos et al., 2018).

Open larval down and back neuron in VFB

Example Images

larval down and back neuron larval down and back neuron larval down and back neuron larval down and back neuron larval down and back neuron

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00047725",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Cholinergic",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00047725",
            "label": "larval down and back neuron"
        },
        "description": [
            "Cholinergic somatosensory interneuron that arborizes in the nociceptive neuropil and receives input from class IV dendritic arborizing neurons (Gerhard et al., 2017; Burgos et al., 2018). From a laterally-located cell body, it projects ventromedially to the nociceptive neuropil and arborizes profusely; then a single process projects back laterally and dorsally towards the cell body (Burgos et al., 2018). It is involved in activating bending and rolling behavior in response to nociceptive stimuli, such as noxious heat (Burgos et al., 2018) and it is a premotor neuron (Zarin et al., 2019)."
        ],
        "comment": [
            "DnBs seem to have peptidergic output sites, but peptide identity unknown (Burgos et al., 2018)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058215",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Cholinergic",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058215",
            "label": "larval cholinergic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00001486",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00001486",
            "label": "3-5I"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00051438",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00051438",
            "label": "larval premotor neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00047726",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Larva",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00047726",
                "label": "larval nociceptive neuropil"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00007275",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00007275",
                "label": "larval multidendritic class IV neuron"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00111225",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Larva",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00111225",
                "label": "cell body rind of larval ventral nerve cord"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002216",
                "label": "capable_of_part_of",
                "type": "capable_of_part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0048266",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0048266",
                "label": "behavioral response to pain"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00101074",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00101074",
                "label": "A09l_a2l Down-and-back-1 (L1EM:3281615)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/1074/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00101074",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00101074",
                    "label": "L1 CNS neuron A09l_a2l Down-and-back-1_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        },
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00101092",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00101092",
                "label": "A09l_a2r Down-and-back-1\t (L1EM:17693220)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/1092/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00101092",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00101092",
                    "label": "L1 CNS neuron A09l_a2r Down-and-back-1\t_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        },
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00101102",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00101102",
                "label": "A09l_a3r Down-and-back-1 (L1EM:1378190)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/1102/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00101102",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00101102",
                    "label": "L1 CNS neuron A09l_a3r Down-and-back-1_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        },
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00101104",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00101104",
                "label": "A09l_a3l Down-and-back-1 (L1EM:2693767)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/1104/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00101104",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00101104",
                    "label": "L1 CNS neuron A09l_a3l Down-and-back-1_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        },
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_00101087",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Individual",
                    "Larva",
                    "Nervous_system",
                    "Neuron",
                    "has_image",
                    "has_neuron_connectivity"
                ],
                "short_form": "VFB_00101087",
                "label": "A09l_t3r Down-and-back-1 (L1EM:10053642)"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00050000",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00050000",
                        "types": [
                            "Entity",
                            "Anatomy",
                            "Individual",
                            "Larva",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00050000",
                        "label": "L1 larval CNS ssTEM - Cardona/Janelia"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/1087/VFB_00050000/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_00101087",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_00101087",
                    "label": "L1 CNS neuron A09l_t3r Down-and-back-1_c"
                },
                "imaging_technique": {
                    "symbol": "TEM",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000258",
                    "label": "transmission electron microscopy (TEM)"
                }
            }
        }
    ],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "DnB neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0238464",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0238464",
                    "label": "Burgos et al., 2018, eLife 7: e26016"
                },
                "FlyBase": "FBrf0238464",
                "PubMed": "29528286",
                "DOI": "10.7554/eLife.26016"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "A09l",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0238464",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0238464",
                    "label": "Burgos et al., 2018, eLife 7: e26016"
                },
                "FlyBase": "FBrf0238464",
                "PubMed": "29528286",
                "DOI": "10.7554/eLife.26016"
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "down-and-back-1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0233076",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0233076",
                    "label": "Zwart et al., 2016, Neuron 91(3): 615--628"
                },
                "FlyBase": "FBrf0233076",
                "PubMed": "27427461",
                "DOI": "10.1016/j.neuron.2016.06.031"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0238464",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0238464",
                "label": "Burgos et al., 2018, eLife 7: e26016"
            },
            "FlyBase": "FBrf0238464",
            "PubMed": "29528286",
            "DOI": "10.7554/eLife.26016"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0244727",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0244727",
                "label": "Zarin et al., 2019, eLife 8: e51781"
            },
            "FlyBase": "",
            "PubMed": "31868582",
            "DOI": "10.7554/eLife.51781"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0237057",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0237057",
                "label": "Gerhard et al., 2017, eLife 6: e29089"
            },
            "FlyBase": "FBrf0237057",
            "PubMed": "29058674",
            "DOI": "10.7554/eLife.29089"
        }
    ]
}