larval Handle-A neuron [FBbt_00111242]
Unpaired interneuron of the larval abdominal neuromere that is part of lineage 0. Its dendritic and axonal domains are located in the medial ventral nerve cord crossing the midline (Ohyama et al., 2015). It receives much of its input from the Basin neurons, with little input from mechanosensory chordotonal neurons (Ohyama et al., 2015; Jovanic et al., 2016). This neuron feeds back to other local interneurons in the Basin circuit via inhibitory GABAergic connections. Originally mis-named as A00b by Ohyama et al. (2015) (FBrf0228257) - the correct synonym is A00b2 (FBrf0239413). Authors of FBrf0228257 and FBrf0233796 do not explicitly state which VNC segments this neuron exists in, therefore, subclasses may not be exhaustive.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen larval Handle-A neuron in VFB
Example Images
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/FBbt_00111242",
"symbol": "",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00111242",
"label": "larval Handle-A neuron"
},
"description": [
"Unpaired interneuron of the larval abdominal neuromere that is part of lineage 0. Its dendritic and axonal domains are located in the medial ventral nerve cord crossing the midline (Ohyama et al., 2015). It receives much of its input from the Basin neurons, with little input from mechanosensory chordotonal neurons (Ohyama et al., 2015; Jovanic et al., 2016). This neuron feeds back to other local interneurons in the Basin circuit via inhibitory GABAergic connections."
],
"comment": [
"Originally mis-named as A00b by Ohyama et al. (2015) (FBrf0228257) - the correct synonym is A00b2 (FBrf0239413). Authors of FBrf0228257 and FBrf0233796 do not explicitly state which VNC segments this neuron exists in, therefore, subclasses may not be exhaustive."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047193",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047193",
"label": "larval feedback local interneuron"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047194",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047194",
"label": "larval Basin neuron"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013001",
"label": "has_synaptic_IO_in",
"type": "has_synaptic_IO_in"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00001102",
"types": [
"Entity",
"Anatomy",
"Class",
"Ganglion",
"Larva",
"Nervous_system"
],
"short_form": "FBbt_00001102",
"label": "larval ventral nerve cord"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002100",
"label": "has soma location",
"type": "has_soma_location"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111264",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system"
],
"short_form": "FBbt_00111264",
"label": "cell body rind of larval abdominal neuromere"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002215",
"label": "capable of",
"type": "capable_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0051932",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0051932",
"label": "synaptic transmission, GABAergic"
}
}
],
"xrefs": [],
"anatomy_channel_image": [
{
"anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00100628",
"types": [
"Entity",
"Anatomy",
"Cell",
"Individual",
"Larva",
"Nervous_system",
"Neuron",
"has_image",
"has_neuron_connectivity"
],
"short_form": "VFB_00100628",
"label": "Handle-A a1 (L1EM:4022794)"
},
"channel_image": {
"image": {
"template_channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00050000",
"types": [
"Entity",
"Individual",
"Template"
],
"short_form": "VFBc_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
},
"index": [],
"template_anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00050000",
"types": [
"Entity",
"Anatomy",
"Individual",
"Larva",
"Nervous_system",
"Template",
"has_image"
],
"short_form": "VFB_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia"
},
"image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/0628/VFB_00050000/"
},
"channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00100628",
"types": [
"Entity",
"Individual"
],
"short_form": "VFBc_00100628",
"label": "L1 CNS neuron Handle-A a1_c"
},
"imaging_technique": {
"symbol": "TEM",
"iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
"types": [
"Entity",
"Class"
],
"short_form": "FBbi_00000258",
"label": "transmission electron microscopy (TEM)"
}
}
}
],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "larval A00b2 neuron",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0233796",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0233796",
"label": "Jovanic et al., 2016, Cell 167(3): 858--870.e19"
},
"FlyBase": "FBrf0233796",
"PubMed": "27720450",
"DOI": "10.1016/j.cell.2016.09.009"
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "fbLN-Ha",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0233796",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0233796",
"label": "Jovanic et al., 2016, Cell 167(3): 858--870.e19"
},
"FlyBase": "FBrf0233796",
"PubMed": "27720450",
"DOI": "10.1016/j.cell.2016.09.009"
}
}
],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0233796",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0233796",
"label": "Jovanic et al., 2016, Cell 167(3): 858--870.e19"
},
"FlyBase": "FBrf0233796",
"PubMed": "27720450",
"DOI": "10.1016/j.cell.2016.09.009"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0239413",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0239413",
"label": "Schneider-Mizell, 2018.5.31, Handle neurons."
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0228257",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0228257",
"label": "Ohyama et al., 2015, Nature 520(7549): 633--639"
},
"FlyBase": "FBrf0228257",
"PubMed": "25896325",
"DOI": "10.1038/nature14297"
}
]
}
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.