larval mushroom body output neuron m1 [FBbt_00047988]
Larval neuron with postsynaptic terminals in multiple ipsilateral mushroom body regions, including the lower two regions of the vertical lobe (V1 and V2) and the lateral appendix (Saumweber et al., 2018). It also has postsynapses in the dorsoanterior compartment (anterior superior medial protocerebrum) (Saumweber et al., 2018). Its presynaptic sites are found in the basocentral compartment (ventromedial cerebrum) and basoposterior medial compartment (lateral accessory lobe) (Saumweber et al., 2018). As well as receiving input from Kenyon cells, it is also synapsed by MBON-e1, MBON-h1, MBON-h2 and MBON-i1 and lateral horn neurons downstream of Or42b projection neurons (Eschbach et al., 2020b). It outputs onto FAN-19, FAN-21 and FAN-22 (Eschbach et al., 2020a). It is GABAergic (Eichler et al., 2017). Its activity inhibits, and its inhibition promotes, turning behavior as part of larval chemotaxis (Eschbach et al., 2020b). MBE20 and CN-62 synonyms from catmaid.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen larval mushroom body output neuron m1 in VFB
Example Images
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/FBbt_00047988",
"symbol": "",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"GABAergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047988",
"label": "larval mushroom body output neuron m1"
},
"description": [
"Larval neuron with postsynaptic terminals in multiple ipsilateral mushroom body regions, including the lower two regions of the vertical lobe (V1 and V2) and the lateral appendix (Saumweber et al., 2018). It also has postsynapses in the dorsoanterior compartment (anterior superior medial protocerebrum) (Saumweber et al., 2018). Its presynaptic sites are found in the basocentral compartment (ventromedial cerebrum) and basoposterior medial compartment (lateral accessory lobe) (Saumweber et al., 2018). As well as receiving input from Kenyon cells, it is also synapsed by MBON-e1, MBON-h1, MBON-h2 and MBON-i1 and lateral horn neurons downstream of Or42b projection neurons (Eschbach et al., 2020b). It outputs onto FAN-19, FAN-21 and FAN-22 (Eschbach et al., 2020a). It is GABAergic (Eichler et al., 2017). Its activity inhibits, and its inhibition promotes, turning behavior as part of larval chemotaxis (Eschbach et al., 2020b)."
],
"comment": [
"MBE20 and CN-62 synonyms from catmaid."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00058217",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"GABAergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00058217",
"label": "larval GABAergic neuron"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047954",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047954",
"label": "larval mushroom body output neuron"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00051207",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00051207",
"label": "larval mushroom body-lateral horn convergence neuron"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00007067",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_domain"
],
"short_form": "FBbt_00007067",
"label": "embryonic/larval lateral accessory lobe"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00007063",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_domain"
],
"short_form": "FBbt_00007063",
"label": "embryonic/larval ventromedial cerebrum"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013009",
"label": "sends_synaptic_output_to_cell",
"type": "sends_synaptic_output_to_cell"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00049029",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00049029",
"label": "larval mushroom body one-step feedback neuron 22"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013009",
"label": "sends_synaptic_output_to_cell",
"type": "sends_synaptic_output_to_cell"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00049026",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00049026",
"label": "larval mushroom body one-step feedback neuron 19"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013009",
"label": "sends_synaptic_output_to_cell",
"type": "sends_synaptic_output_to_cell"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00049028",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00049028",
"label": "larval mushroom body one-step feedback neuron 21"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00110199",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00110199",
"label": "V1 segment of the vertical lobe"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00110190",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00110190",
"label": "lateral appendix of larval mushroom body"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00007065",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00007065",
"label": "embryonic/larval anterior superior medial protocerebrum"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00110198",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00110198",
"label": "V2 segment of the vertical lobe"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047981",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"GABAergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047981",
"label": "larval mushroom body output neuron h2"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047972",
"types": [
"Entity",
"Anatomy",
"Cell",
"Cholinergic",
"Class",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047972",
"label": "larval mushroom body output neuron e1"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047982",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"Glutamatergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047982",
"label": "larval mushroom body output neuron i1"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047980",
"types": [
"Entity",
"Anatomy",
"Cell",
"Class",
"GABAergic",
"Larva",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00047980",
"label": "larval mushroom body output neuron h1"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00001919",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system"
],
"short_form": "FBbt_00001919",
"label": "embryonic/larval central nervous system"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002100",
"label": "has soma location",
"type": "has_soma_location"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00111226",
"types": [
"Entity",
"Anatomy",
"Class",
"Larva",
"Nervous_system"
],
"short_form": "FBbt_00111226",
"label": "cell body rind of larval brain"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002216",
"label": "capable_of_part_of",
"type": "capable_of_part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0007635",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0007635",
"label": "chemosensory behavior"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002216",
"label": "capable_of_part_of",
"type": "capable_of_part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0035179",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0035179",
"label": "larval turning behavior"
}
}
],
"xrefs": [],
"anatomy_channel_image": [
{
"anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00100210",
"types": [
"Entity",
"Anatomy",
"Cell",
"GABAergic",
"Individual",
"Larva",
"Nervous_system",
"Neuron",
"has_image",
"has_neuron_connectivity"
],
"short_form": "VFB_00100210",
"label": "CN-62 (L1EM:4022539)"
},
"channel_image": {
"image": {
"template_channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00050000",
"types": [
"Entity",
"Individual",
"Template"
],
"short_form": "VFBc_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
},
"index": [],
"template_anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00050000",
"types": [
"Entity",
"Anatomy",
"Individual",
"Larva",
"Nervous_system",
"Template",
"has_image"
],
"short_form": "VFB_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia"
},
"image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/0210/VFB_00050000/"
},
"channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00100210",
"types": [
"Entity",
"Individual"
],
"short_form": "VFBc_00100210",
"label": "L1 CNS neuron MBE20 right_c"
},
"imaging_technique": {
"symbol": "TEM",
"iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
"types": [
"Entity",
"Class"
],
"short_form": "FBbi_00000258",
"label": "transmission electron microscopy (TEM)"
}
}
},
{
"anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00100507",
"types": [
"Entity",
"Anatomy",
"Cell",
"GABAergic",
"Individual",
"Larva",
"Nervous_system",
"Neuron",
"has_image",
"has_neuron_connectivity"
],
"short_form": "VFB_00100507",
"label": "CN-62 (L1EM:17016974)"
},
"channel_image": {
"image": {
"template_channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00050000",
"types": [
"Entity",
"Individual",
"Template"
],
"short_form": "VFBc_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia_c"
},
"index": [],
"template_anatomy": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFB_00050000",
"types": [
"Entity",
"Anatomy",
"Individual",
"Larva",
"Nervous_system",
"Template",
"has_image"
],
"short_form": "VFB_00050000",
"label": "L1 larval CNS ssTEM - Cardona/Janelia"
},
"image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/0507/VFB_00050000/"
},
"channel": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/VFBc_00100507",
"types": [
"Entity",
"Individual"
],
"short_form": "VFBc_00100507",
"label": "L1 CNS neuron MBE20 left_c"
},
"imaging_technique": {
"symbol": "TEM",
"iri": "http://purl.obolibrary.org/obo/FBbi_00000258",
"types": [
"Entity",
"Class"
],
"short_form": "FBbi_00000258",
"label": "transmission electron microscopy (TEM)"
}
}
}
],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "larval MBE20",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "larval MBON-m1",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0238440",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0238440",
"label": "Saumweber et al., 2018, Nat. Commun. 9(1): 1104"
},
"FlyBase": "",
"PubMed": "29549237",
"DOI": "10.1038/s41467-018-03130-1"
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "CN-62",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0236359",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0236359",
"label": "Eichler et al., 2017, Nature 548(7666): 175--182"
},
"FlyBase": "FBrf0236359",
"PubMed": "28796202",
"DOI": "10.1038/nature23455"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0238440",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0238440",
"label": "Saumweber et al., 2018, Nat. Commun. 9(1): 1104"
},
"FlyBase": "",
"PubMed": "29549237",
"DOI": "10.1038/s41467-018-03130-1"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0245294",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0245294",
"label": "Eschbach et al., 2020, Nat. Neurosci. 23(4): 544--555"
},
"FlyBase": "FBrf0245294",
"PubMed": "32203499",
"DOI": "10.1038/s41593-020-0607-9"
}
]
}
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.