medullary intrinsic neuron Mi1 [FBbt_00003776]

Medullary intrinsic narrow field neuron with bushy, fine arborizations in medulla layers M1, M5-6 and M9-10, coinciding with the arborization domains of lamina monopolar neuron L1. The projection of this neuron branches at the inner-face of the medulla to form two to three varicose recurrent terminal specializations that extend back up to the inner border of layer M8 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). Pre-synaptic terminals are present in medulla layers M9-M10. It receives input from lamina monopolar neurons L1 and L5, centrifugal neuron C2 and photoreceptor cell R8 (Takemura et al., 2013). It outputs to T neuron T4 and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Hasegawa et al., 2011). Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt}) [FBtp0015803]. The neurotransmitter was assessed by labelling cells with an anti-ChAT antibody (Hasegawa et al., 2011). The morphology of the terminals was judged from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity and morphology in the medulla were assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013).

Open medullary intrinsic neuron Mi1 in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003776",
            "symbol": "Mi1",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Cholinergic",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003776",
            "label": "medullary intrinsic neuron Mi1"
        },
        "description": [
            "Medullary intrinsic narrow field neuron with bushy, fine arborizations in medulla layers M1, M5-6 and M9-10, coinciding with the arborization domains of lamina monopolar neuron L1. The projection of this neuron branches at the inner-face of the medulla to form two to three varicose recurrent terminal specializations that extend back up to the inner border of layer M8 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). Pre-synaptic terminals are present in medulla layers M9-M10. It receives input from lamina monopolar neurons L1 and L5, centrifugal neuron C2 and photoreceptor cell R8 (Takemura et al., 2013). It outputs to T neuron T4 and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Hasegawa et al., 2011)."
        ],
        "comment": [
            "Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt}) [FBtp0015803]. The neurotransmitter was assessed by labelling cells with an anti-ChAT antibody (Hasegawa et al., 2011). The morphology of the terminals was judged from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity and morphology in the medulla were assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "Mi",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003775",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003775",
            "label": "medullary intrinsic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110136",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110136",
            "label": "narrow field columnar neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058205",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Cholinergic",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058205",
            "label": "adult cholinergic neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003760",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003760",
                "label": "medulla layer M10"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003750",
                "label": "medulla layer M1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003754",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003754",
                "label": "medulla layer M5"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003755",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003755",
                "label": "medulla layer M6"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003759",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003759",
                "label": "medulla layer M9"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "Tm3",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003791",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "GABAergic",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003791",
                "label": "transmedullary neuron Tm3a"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "T4",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003731",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003731",
                "label": "T neuron T4"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003750",
                "label": "medulla layer M1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003754",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003754",
                "label": "medulla layer M5"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003755",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003755",
                "label": "medulla layer M6"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "L5",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003725",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003725",
                "label": "lamina monopolar neuron L5"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "C2",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003743",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "GABAergic",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003743",
                "label": "centrifugal neuron C2"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R8",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004227",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004227",
                "label": "photoreceptor cell R8"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "L1",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003719",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Glutamatergic",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003719",
                "label": "lamina monopolar neuron L1"
            }
        }
    ],
    "xrefs": [
        {
            "link_base": "https://flybrain-ndb.virtualflybrain.org/neuronrec-",
            "site": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/FlyBrain_NDB",
                "types": [
                    "Entity",
                    "Individual",
                    "Site"
                ],
                "short_form": "FlyBrain_NDB",
                "label": "FlyBrain NeuronDB"
            },
            "is_data_source": false,
            "link_postfix": [
                ".html"
            ],
            "icon": "http://flybrain-ndb.virtualflybrain.org/NDB_title260.gif",
            "accession": "10097",
            "link_text": "medullary intrinsic neuron Mi1 on FlyBrain NeuronDB",
            "homepage": "https://flybrain-ndb.virtualflybrain.org"
        }
    ],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "small field unilateral tristratified neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "medullary intrinsic neuron 1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "Sut",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0222324",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0222324",
                "label": "Takemura et al., 2013, Nature 500(7461): 175--181"
            },
            "FlyBase": "",
            "PubMed": "23925240",
            "DOI": "10.1038/nature12450"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0204652",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0204652",
                "label": "Morante and Desplan, 2008, Curr. Biol. 18(8): 553--565"
            },
            "FlyBase": "",
            "PubMed": "18403201",
            "DOI": "10.1016/j.cub.2008.02.075"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0049410",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0049410",
                "label": "Fischbach and Dittrich, 1989, Cell Tissue Res. 258(3): 441--475"
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0213020",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0213020",
                "label": "Hasegawa et al., 2011, Development 138(5): 983--993"
            },
            "FlyBase": "",
            "PubMed": "21303851",
            "DOI": "10.1242/dev.058370"
        }
    ]
}