medullary intrinsic neuron Mi4 [FBbt_00003779]
Medullary intrinsic narrow field neuron with both fine and bleb-type arborizations in medulla layers M1, M2, M3 and M8, but with only fine arborizations in medulla layers M4 and M5, and only bleb-type arborizations in medulla layer M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It receives input from the lamina monopolar neuron L5 and photoreceptor R8 (Takemura et al., 2013). It is a GABAergic neuron (Takemura et al., 2017). Raghu and Borst (2011) identified this as glutamatergic using a vGlut[CNSIII]-GAL4 driver [FBti0129148], but vGlut antibody staining performed by Takemura et al. (2017) was not strong compared to neighboring cells, whereas GAD1 staining was strong. Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013).
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen medullary intrinsic neuron Mi4 in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/FBbt_00003779",
"symbol": "Mi4",
"types": [
"Entity",
"Adult",
"Anatomy",
"Cell",
"Class",
"GABAergic",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00003779",
"label": "medullary intrinsic neuron Mi4"
},
"description": [
"Medullary intrinsic narrow field neuron with both fine and bleb-type arborizations in medulla layers M1, M2, M3 and M8, but with only fine arborizations in medulla layers M4 and M5, and only bleb-type arborizations in medulla layer M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It receives input from the lamina monopolar neuron L5 and photoreceptor R8 (Takemura et al., 2013). It is a GABAergic neuron (Takemura et al., 2017)."
],
"comment": [
"Raghu and Borst (2011) identified this as glutamatergic using a vGlut[CNSIII]-GAL4 driver [FBti0129148], but vGlut antibody staining performed by Takemura et al. (2017) was not strong compared to neighboring cells, whereas GAD1 staining was strong. Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013)."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00058207",
"types": [
"Entity",
"Adult",
"Anatomy",
"Cell",
"Class",
"GABAergic",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00058207",
"label": "adult GABAergic neuron"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00110136",
"types": [
"Entity",
"Adult",
"Anatomy",
"Cell",
"Class",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00110136",
"label": "narrow field columnar neuron"
},
{
"symbol": "Mi",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003775",
"types": [
"Entity",
"Adult",
"Anatomy",
"Cell",
"Class",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00003775",
"label": "medullary intrinsic neuron"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003759",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003759",
"label": "medulla layer M9"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003750",
"label": "medulla layer M1"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003752",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003752",
"label": "medulla layer M3"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003751",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003751",
"label": "medulla layer M2"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013003",
"label": "sends_synaptic_output_to_region",
"type": "sends_synaptic_output_to_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003758",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003758",
"label": "medulla layer M8"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003754",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003754",
"label": "medulla layer M5"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003751",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003751",
"label": "medulla layer M2"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003752",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003752",
"label": "medulla layer M3"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003750",
"label": "medulla layer M1"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003758",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003758",
"label": "medulla layer M8"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013002",
"label": "receives synaptic input in region",
"type": "receives_synaptic_input_in_region"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003753",
"types": [
"Entity",
"Adult",
"Anatomy",
"Class",
"Nervous_system",
"Synaptic_neuropil",
"Synaptic_neuropil_subdomain"
],
"short_form": "FBbt_00003753",
"label": "medulla layer M4"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "L5",
"iri": "http://purl.obolibrary.org/obo/FBbt_00003725",
"types": [
"Entity",
"Adult",
"Anatomy",
"Cell",
"Cholinergic",
"Class",
"Nervous_system",
"Neuron"
],
"short_form": "FBbt_00003725",
"label": "lamina monopolar neuron L5"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
},
"object": {
"symbol": "R8",
"iri": "http://purl.obolibrary.org/obo/FBbt_00004227",
"types": [
"Entity",
"Adult",
"Anatomy",
"Cell",
"Cholinergic",
"Class",
"Nervous_system",
"Neuron",
"Sensory_neuron"
],
"short_form": "FBbt_00004227",
"label": "photoreceptor cell R8"
}
}
],
"xrefs": [
{
"link_base": "https://flybrain-ndb.virtualflybrain.org/neuronrec-",
"site": {
"symbol": "",
"iri": "http://virtualflybrain.org/reports/FlyBrain_NDB",
"types": [
"Entity",
"Individual",
"Site"
],
"short_form": "FlyBrain_NDB",
"label": "FlyBrain NeuronDB"
},
"is_data_source": false,
"link_postfix": [
".html"
],
"icon": "http://flybrain-ndb.virtualflybrain.org/NDB_title260.gif",
"accession": "10103",
"link_text": "medullary intrinsic neuron Mi4 on FlyBrain NeuronDB",
"homepage": "https://flybrain-ndb.virtualflybrain.org"
}
],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "Mi4",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0222324",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0222324",
"label": "Takemura et al., 2013, Nature 500(7461): 175--181"
},
"FlyBase": "",
"PubMed": "23925240",
"DOI": "10.1038/nature12450"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0213690",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0213690",
"label": "Raghu and Borst, 2011, PLoS ONE 6(5): e19472"
},
"FlyBase": "",
"PubMed": "21573163",
"DOI": "10.1371/journal.pone.0019472"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0204652",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0204652",
"label": "Morante and Desplan, 2008, Curr. Biol. 18(8): 553--565"
},
"FlyBase": "",
"PubMed": "18403201",
"DOI": "10.1016/j.cub.2008.02.075"
},
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/FBrf0049410",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "FBrf0049410",
"label": "Fischbach and Dittrich, 1989, Cell Tissue Res. 258(3): 441--475"
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.