midgut enterocyte [FBbt_00047177]

Specialized epithelial cell of the midgut. A large, polyploid, cuboidal or low-columnar epithelial cell with its nucleus in the middle and a mass of microvilli (brush border) on its apical surface. On its basal side, extensive infoldings of the plasma membrane form a labyrinth which fills the lower half of the cell. It is attached to adjacent enterocytes by smooth septate junctions. Can be identified in adults and larvae based on expression of nubbin, Myosin31DF (Sawyer et al., 2017) and mex1 (Phillips and Thomas, 2006 - FBrf0190960; Chen et al., 2014 - FBrf0226781).

Open midgut enterocyte in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00047177",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00047177",
            "label": "midgut enterocyte"
        },
        "description": [
            "Specialized epithelial cell of the midgut. A large, polyploid, cuboidal or low-columnar epithelial cell with its nucleus in the middle and a mass of microvilli (brush border) on its apical surface. On its basal side, extensive infoldings of the plasma membrane form a labyrinth which fills the lower half of the cell. It is attached to adjacent enterocytes by smooth septate junctions."
        ],
        "comment": [
            "Can be identified in adults and larvae based on expression of nubbin, Myosin31DF (Sawyer et al., 2017) and mex1 (Phillips and Thomas, 2006 - FBrf0190960; Chen et al., 2014 - FBrf0226781)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00007042",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00007042",
            "label": "enterocyte"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00047109",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class"
                ],
                "short_form": "FBbt_00047109",
                "label": "midgut epithelium"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00005383",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class"
                ],
                "short_form": "FBbt_00005383",
                "label": "midgut"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0086347",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgn0086347",
                "label": "Myo31DF"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0004228",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgn0004228",
                "label": "mex1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0085424",
                "types": [
                    "Entity",
                    "Class",
                    "Feature"
                ],
                "short_form": "FBgn0085424",
                "label": "nub"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "midgut EC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    ],
                    "short_form": "FBrf0191251",
                    "label": "Ohlstein and Spradling, 2006, Nature 439(7075): 470--474"
                },
                "FlyBase": "",
                "PubMed": "16340960",
                "DOI": "10.1038/nature04333"
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "absorptive cell",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0206835",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0206835",
                    "label": "Maeda et al., 2008, Genes Cells 13(12): 1219--1227"
                },
                "FlyBase": "",
                "PubMed": "19021776",
                "DOI": "10.1111/j.1365-2443.2008.01239.x"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0007735",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0007735",
                "label": "Miller, 1950, Demerec, 1950: 420--534"
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0139657",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0139657",
                "label": "Baumann, 2001, Exp. Cell Res. 270(2): 176--187"
            },
            "FlyBase": "",
            "PubMed": "11640882",
            "DOI": "10.1006/excr.2001.5343"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0191251",
                "types": [
                    "Entity",
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                ],
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            },
            "FlyBase": "",
            "PubMed": "16340960",
            "DOI": "10.1038/nature04333"
        }
    ]
}