peripheral cell [FBbt_00110875]

A cell in the larval midgut and early pupal midgut that extends its processes around the midgut imaginal islands (Mathur et al., 2010). These cells are formed at late second larval instar, usually by the first, asymmetric, division of an adult midgut progenitor cell (AMP) (Mathur et al., 2010). There is usually one peripheral cell per imaginal island (Mathur et al., 2010). These cells undergo apoptosis shortly after pupariation (0-2h APF) and do not contribute to the adult midgut (Mathur et al., 2010). Peripheral cells act as a niche for AMPs to keep them undifferentiated until metamorphosis (Mathur et al., 2010). These cells can be identified by their expression of a Su(H)GBE reporter, indicating active Notch signalling (Mathur et al., 2010).
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Open peripheral cell in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110875",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva"
            ],
            "short_form": "FBbt_00110875",
            "label": "peripheral cell"
        },
        "description": [
            "A cell in the larval midgut and early pupal midgut that extends its processes around the midgut imaginal islands (Mathur et al., 2010). These cells are formed at late second larval instar, usually by the first, asymmetric, division of an adult midgut progenitor cell (AMP) (Mathur et al., 2010). There is usually one peripheral cell per imaginal island (Mathur et al., 2010). These cells undergo apoptosis shortly after pupariation (0-2h APF) and do not contribute to the adult midgut (Mathur et al., 2010). Peripheral cells act as a niche for AMPs to keep them undifferentiated until metamorphosis (Mathur et al., 2010)."
        ],
        "comment": [
            "These cells can be identified by their expression of a Su(H)GBE reporter, indicating active Notch signalling (Mathur et al., 2010)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00001886",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Larva"
            ],
            "short_form": "FBbt_00001886",
            "label": "embryonic/larval midgut cell"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00001837",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class",
                    "Larva"
                ],
                "short_form": "FBbt_00001837",
                "label": "midgut imaginal island"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002202",
                "label": "develops from",
                "type": "develops_from"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00000449",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Larva"
                ],
                "short_form": "FBbt_00000449",
                "label": "adult midgut progenitor cell"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "PC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0209706",
                    "types": [
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                    ],
                    "short_form": "FBrf0209706",
                    "label": "Mathur et al., 2010, Science 327(5962): 210--213"
                },
                "FlyBase": "",
                "PubMed": "20056890",
                "DOI": "10.1126/science.1181958"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "niche peripheral cell",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0212138",
                    "types": [
                        "Entity",
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                    ],
                    "short_form": "FBrf0212138",
                    "label": "Zeng et al., 2010, genesis 48(10): 607--611"
                },
                "FlyBase": "",
                "PubMed": "20681020",
                "DOI": "10.1002/dvg.20661"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
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                "short_form": "FBrf0209706",
                "label": "Mathur et al., 2010, Science 327(5962): 210--213"
            },
            "FlyBase": "",
            "PubMed": "20056890",
            "DOI": "10.1126/science.1181958"
        }
    ]
}