Roc1a [FBgn0025638]

[zinc ion binding; EG:115C2.11; Negative Regulators of Hedgehog Signaling Pathway; dRoc1; SCF-betaTrCP complex; SCF-βTrCP complex; enables; material entity; KBTBD7:CUL3:RBX1 ubiquitinates NF1; ROC UBIQUITIN LIGASES; Roc1α; CK01110; cullin family protein binding; CG16982; Negative Regulators of Wnt-TCF Signaling Pathway; Negative Regulators of Insulin-like Receptor Signaling Pathway; Regulator of cullins 1a; NEDD8 ligase activity; BEST:CK01110; Roc1alpha; Roc1a; anon-EST:Posey65; Rbx1/Roc; ROC1; NEDD8 TRANSFERASES; is part of; gene; roc1a; dRoc1a; VCB COMPLEX; SCF-SLMB UBIQUITIN LIGASE COMPLEX; dRbx1]

Open Roc1a in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://flybase.org/reports/FBgn0025638",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "Gene"
            ],
            "short_form": "FBgn0025638",
            "label": "Roc1a"
        },
        "description": [],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/BFO_0000040",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "BFO_0000040",
            "label": "material entity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/SO_0000704",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "SO_0000704",
            "label": "gene"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002327",
                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0008270",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0008270",
                "label": "zinc ion binding"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002327",
                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0097602",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0097602",
                "label": "cullin family protein binding"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002327",
                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0061630",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0061630",
                "label": "KBTBD7:CUL3:RBX1 ubiquitinates NF1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002327",
                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0061663",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0061663",
                "label": "NEDD8 ligase activity"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0000891",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0000891",
                "label": "Negative Regulators of Wnt-TCF Signaling Pathway"
            }
        },
        {
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                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0000062",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0000062",
                "label": "ROC UBIQUITIN LIGASES"
            }
        },
        {
            "relation": {
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                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0000900",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0000900",
                "label": "Negative Regulators of Insulin-like Receptor Signaling Pathway"
            }
        },
        {
            "relation": {
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                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0001219",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0001219",
                "label": "NEDD8 TRANSFERASES"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0000980",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0000980",
                "label": "Negative Regulators of Hedgehog Signaling Pathway"
            }
        },
        {
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                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0000894",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0000894",
                "label": "SCF-SLMB UBIQUITIN LIGASE COMPLEX"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
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                "iri": "http://flybase.org/reports/FBgg0001732",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0001732",
                "label": "VCB COMPLEX"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "EG:115C2.11",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "SCF-\u03b2TrCP complex",
                "type": ""
            },
            "pub": {
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "anon-EST:Posey65",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "CK01110",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "CG16982",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dRoc1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Rbx1/Roc",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dRoc1a",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dRbx1",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Roc",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Roc1alpha",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Roc1",
                "type": ""
            },
            "pub": {
                "core": {
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                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "roc1a",
                "type": ""
            },
            "pub": {
                "core": {
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Roc1a",
                "type": ""
            },
            "pub": {
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "BEST:CK01110",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Regulator of cullins 1a",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Roc1\u03b1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "SCF-betaTrCP complex",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Rbx1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ROC1",
                "type": ""
            },
            "pub": {
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}