T neuron T4 [FBbt_00003731]
T neuron whose cell body fiber projects through the lobula plate with little or no arborization before bifurcating in the second optic chiasm with one branch forming a fine terminal arborization in medulla layer M9 and M10 and the other branch doubling back to form bleb-type arborizations in the lobula plate. It receives strong input from the medullary intrinsic neuron Mi1 and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018). Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013). The neurotransmitter was assessed with a split-GAL4 strategy using a Chat-DBD allele (FBal0198074) (Mauss et al., 2014) and single-cell transcript profiling (Shinomiya et al., 2014).
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerVFB Term Json
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"T neuron whose cell body fiber projects through the lobula plate with little or no arborization before bifurcating in the second optic chiasm with one branch forming a fine terminal arborization in medulla layer M9 and M10 and the other branch doubling back to form bleb-type arborizations in the lobula plate. It receives strong input from the medullary intrinsic neuron Mi1 and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018)."
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"comment": [
"Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013). The neurotransmitter was assessed with a split-GAL4 strategy using a Chat-DBD allele (FBal0198074) (Mauss et al., 2014) and single-cell transcript profiling (Shinomiya et al., 2014)."
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"query": "Get JSON for Class",
"version": "44725ae",
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"iri": "http://purl.obolibrary.org/obo/FBbt_00003726",
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"short_form": "FBbt_00058205",
"label": "adult cholinergic neuron"
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"label": "sends_synaptic_output_to_region",
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"iri": "http://purl.obolibrary.org/obo/FBbt_00003791",
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"label": "transmedullary neuron Tm3a"
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"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0013008",
"label": "receives synaptic input from neuron",
"type": "receives_synaptic_input_from_neuron"
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"object": {
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"iri": "http://purl.obolibrary.org/obo/FBbt_00003776",
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"short_form": "FBbt_00003776",
"label": "medullary intrinsic neuron Mi1"
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"label": "develops from",
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"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/FBbt_00047992",
"types": [
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],
"short_form": "FBbt_00047992",
"label": "type III neuroblast"
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"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "T4",
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"iri": "http://flybase.org/reports/FBrf0237184",
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"short_form": "FBrf0237184",
"label": "Klapoetke et al., 2017, Nature 551(7679): 237--241"
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