transmedullary neuron Tm5c [FBbt_00110074]

Subtype of the transmedullary neuron Tm5. It extends multiple fine dendritic processes that span around eight medulla columns in the M1, M3 and M6 layers. Its axon often bifurcates in lobula layer 4 to terminate in layers 4 to 6. Arbors are found both in columns that contain the photoreceptor axons of yellow and pale ommatidia. It receives input from the photoreceptor cell R8, mostly from terminals in layer M3, but also in M1 and M2, and from the distal medullary amacrine neuron Dm8 in layer M6 (Karuppudurai et al., 2014). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It differs from the subtypes Tm5a and Tm5b by its arborization pattern by arborizing in medulla layer M1. It is a glutamatergic neuron (Gao et al., 2008; Karuppudurai et al., 2014). The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P{GawB}vGlut[OK371] [FBti0076967] (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity inferred from GRASP experiments (Karuppudurai et al., 2014; Lin et al., 2016), from EM reconstructions from a single EM section (inferred by curator to be Tm5c subtype based on evidence from other studies) (Gao et al., 2008) or from double-labeling EM (Lin et al., 2016).

Open transmedullary neuron Tm5c in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110074",
            "symbol": "Tm5c",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Glutamatergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110074",
            "label": "transmedullary neuron Tm5c"
        },
        "description": [
            "Subtype of the transmedullary neuron Tm5. It extends multiple fine dendritic processes that span around eight medulla columns in the M1, M3 and M6 layers. Its axon often bifurcates in lobula layer 4 to terminate in layers 4 to 6. Arbors are found both in columns that contain the photoreceptor axons of yellow and pale ommatidia. It receives input from the photoreceptor cell R8, mostly from terminals in layer M3, but also in M1 and M2, and from the distal medullary amacrine neuron Dm8 in layer M6 (Karuppudurai et al., 2014). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It differs from the subtypes Tm5a and Tm5b by its arborization pattern by arborizing in medulla layer M1. It is a glutamatergic neuron (Gao et al., 2008; Karuppudurai et al., 2014)."
        ],
        "comment": [
            "The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P{GawB}vGlut[OK371] [FBti0076967] (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity inferred from GRASP experiments (Karuppudurai et al., 2014; Lin et al., 2016), from EM reconstructions from a single EM section (inferred by curator to be Tm5c subtype based on evidence from other studies) (Gao et al., 2008) or from double-labeling EM (Lin et al., 2016)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058208",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Glutamatergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058208",
            "label": "adult glutamatergic neuron"
        },
        {
            "symbol": "Tm5",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003793",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003793",
            "label": "transmedullary neuron Tm5"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00040017",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00040017",
                "label": "lobula layer 6"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003856",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003856",
                "label": "lobula layer 4"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00111516",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00111516",
                "label": "lobula intrinsic neuron Li4"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003750",
                "label": "medulla layer M1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "Dm8",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00013774",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Glutamatergic",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00013774",
                "label": "distal medullary amacrine neuron Dm8"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R8",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004227",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004227",
                "label": "photoreceptor cell R8"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Tm5c",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0247762",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0247762",
                    "label": "\u00d6zel et al., 2021, Nature 589(7840): 88--95"
                },
                "FlyBase": "",
                "PubMed": "33149298",
                "DOI": "10.1038/s41586-020-2879-3"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0049410",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0049410",
                "label": "Fischbach and Dittrich, 1989, Cell Tissue Res. 258(3): 441--475"
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0206213",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0206213",
                "label": "Gao et al., 2008, Neuron 60(2): 328--342"
            },
            "FlyBase": "",
            "PubMed": "18957224",
            "DOI": "10.1016/j.neuron.2008.08.010"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0230403",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0230403",
                "label": "Lin et al., 2016, J. Comp. Neurol. 524(2): 213--227"
            },
            "FlyBase": "",
            "PubMed": "26179639",
            "DOI": "10.1002/cne.23857"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0224070",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0224070",
                "label": "Karuppudurai et al., 2014, Neuron 81(3): 603--615"
            },
            "FlyBase": "",
            "PubMed": "24507194",
            "DOI": "10.1016/j.neuron.2013.12.010"
        }
    ]
}